Patent · US Expired

Thiadiazoles and antipicornaviral compositions

US5453433A · kind A · utility

9Cited by
1References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 13, 1994
Grant dateSep 26, 1995
Priority date
Expiry dateMay 13, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the formula; ##STR1## wherein: Thi is thiadiazolyl or substituted thiadiazolyl; PA1 Y is alkylene bridge of 3-9 carbon atoms; PA1 R.sub.1 and R.sub.2 are each independently chosen from hydrogen, halo, alkyl, alkenyl, amino, alkylthio, hydroxy, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl, alkylsulfinyl alkyl, alkylsulfonylalkyl, alkoxy, nitro, carboxy, alkoxycarbonyl, dialkylaminoalkyl, alkylaminoalkyl, aminoalkyl, difluoromethyl, trifluoromethyl, or cyano; PA1 R.sub.3 is alkoxycarbonyl, phenyl, alkyltetrazolyl, or heterocyclyl; or a pharmaceutically acceptable salt thereof are effective antipicornaviral agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.