Bicyclic .beta.-lactams intermediates having a new amino protecting group
US5453504A · kind A · utility
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Key dates
| Filing date | Sep 21, 1994 |
| Grant date | Sep 26, 1995 |
| Priority date | — |
| Expiry date | Sep 21, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for preparing a new class of protected amino intermediates is provided which utilizes reaction of an imido protected primary amine with a secondary amine. The intermediates thus provided are suitably protected for nucleophilic functionalization on the residue of the primary amine. The desired imido protected amine thus derivatized may be regenerated using acid. Further provided are methods for resolving racemic primary amines. Also provided are .beta.-lactam intermediates protected with the new amino protecting group which are useful in the preparation of .beta.-lactam antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.