Patent · US Expired

Strand displacement amplification

US5455166A · kind A · utility

848Cited by
3References
29Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJan 9, 1992
Grant dateOct 3, 1995
Priority date
Expiry dateJan 9, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6853
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This invention relates a nucleic acid target amplification and detection method which operates at a single temperature and makes use of a polymerase in conjunction with an endonuclease that will nick the polymerized strand such that the polymerase will displace the strand without digestion while generating a newly polymerized strand.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.