Patent · US Expired

Biologically active lipoprotein and its use

US5455227A · kind A · utility

7Cited by

11References

7Claims

0Family size

Assignee

KabiGen AB · SE

Inventors

Tore Curstedt · Sollentuna, SE
Hans Jornvall · Mölndal, SE
Bjorn Lowenadler · Täby, SE
Bengt Robertsson · Stockholm, SE

Key dates

Filing date	May 21, 1993
Grant date	Oct 3, 1995
Priority date	—
Expiry date	May 21, 2013

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A lipoprotein possessing pulmonary surfactant activity comprising an alveolar polypeptide or protein and, covalently bound thereto, one or two fatty acid residue(s); PA1 a pharmaceutical composition comprising such lipoprotein and a phospholipid type of material; and PA1 a method of facilitating respiration in mammals including man, comprising administering an effective amount of such a lipoprotein or pharmaceutical composition to the respiratory tract of a patient subject to respiratory disorder so as to reduce surface tension at the air-liquid interface of the patient's alveoli.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.