Method for minimizing and containing ischemic and reperfusion injury
US5455229A · kind A · utility
13Cited by
1References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1992 |
| Grant date | Oct 3, 1995 |
| Priority date | — |
| Expiry date | Dec 23, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a method for minimizing and containing injury caused when tissue is subject to ischemia and reperfusion. The method comprises administering certain derivatized tripeptide arginal compounds concurent with, or immediately after, reestablishing blood flow to the ischemic tissue. The method is particularly useful for minimizing and containing damage to the heart during evolving myocardial infarction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.