2-pyrrolidinones, pharmaceutical compositions containing these compounds and processes for preparing them

US5455348A · kind A · utility

Assignee

• Karl Thomae · DE

Inventors

• Volkhard Austel · Biberach, DE
• Wolfgang Eisert · Biberach, DE
• Frank Himmelsbach · Mittelbiberach, DE
• Guenter Linz · Mittelbiberach, DE
• Thomas Mueller · Zell am Harmersbach, DE
• Helmut Pieper · Lohr am Main, DE
• Johannes Weisenberger · Biberach, DE

Key dates

• Filing date: Dec 23, 1993
• Grant date: Oct 3, 1995
• Expiry date: Dec 23, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to cyclic imino derivatives of general formula EQU B--X.sub.5 --X.sub.4 --X.sub.3 --X.sub.2 --X.sub.1 --A--Y--E(I) wherein PA1 A, B, E, X.sub.2 to X.sub.5 and Y are defined as in claim 1, the stereoisomers, tautomers, mixtures and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, preferably aggregation-inhibiting effects, pharmaceutical compositions which contain these compounds and processes for preparing them.