Patent · US Expired

Method for making a bioerodible material for the sustained release of a medicament and the material made from the method

US5456917A · kind A · utility

1,011Cited by
28References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 12, 1994
Grant dateOct 10, 1995
Priority date
Expiry dateJan 12, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/1647
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for making an implantable bioerodible material for the sustained release of a medicament and the material made from the method. The method comprises the formulation of a biomaterial polymeric carrier into particles of predetermined density and size. The particles are then are mixed with the desired medicament and extruded into the desired shape for implantation or reground to a predetermined size distribution for injection as a suspension. In an alternative embodiment, the particles of polymeric carrier are immersed in a solvent containing a medicament, and the pores of the particles are filled with medicament through alternate application and release of vacuum.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.