Isolation of fetal erythrocytes
US5457024A · kind A · utility
52Cited by
13References
14Claims
0Family size
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Key dates
| Filing date | Jan 22, 1993 |
| Grant date | Oct 10, 1995 |
| Priority date | — |
| Expiry date | Jan 22, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for isolating nucleated fetal erythrocytes (NFEs) from a maternal blood sample by separating erythrocytes in the maternal blood sample from all other nucleated cells therein using a leukocyte depletion device; and isolating NFEs from nonnucleated maternal erythrocytes. Preferably the maternal blood is peripheral maternal blood. The isolated NFEs can then be analyzed for genetic disorders and the like, such as by in situ hybridization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.