Rare earth macrocyclic complexes and use thereof for reduction of disturbances in an assay using fluorescence
US5457184A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 25, 1994 |
| Grant date | Oct 10, 1995 |
| Priority date | — |
| Expiry date | Feb 25, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2458/40
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to macrocyclic rare earth complexes which consist of at least one rare earth salt complexed by a macrocyclic compound of formula (I): ##STR1## in which: the bivalent radicals A, B, C and D, which are identical or different, are hydrocarbon chains optionally containing one or more heteroatoms, at least one of said radicals containing at least one molecular unit or essentially consisting of a molecular unit possessing a triplet energy greater than the energy of the emission level of the complexed rare earth ion, at least one of said radicals consisting of a substituted or unsubstituted nitrogen-containing heterocyclic system in which at least one of the nitrogen atoms carries an oxy group, and it being possible for one of the radicals C or D not to exist; and PA0 X.sub.1 and X.sub.2, which are identical or different, are hydrogen or a hydrocarbon chain (CH.sub.2).sub.n optionally interrupted by 1 or more heteroatoms, n being an integer from 1 to 10, with the proviso that if the radicals A and/or B are a nitrogen-containing heterocyclic system in which at least one of the nitrogen atoms carries an oxy group, the radicals C and/or D are selected from biquinolines,…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.