Patent · US Expired

Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-CoA reductase inhibitors

US5457227A · kind A · utility

10Cited by
12References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 8, 1993
Grant dateOct 10, 1995
Priority date
Expiry dateOct 8, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C69/716
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel, overall process for the preparation of a compound of the formula I: ##STR1## where R.sup.1 and R.sup.2 are each independently hydrogen, an alkyl group, a cycloalkyl group, an aryl group or, taken together with the carbon atom to which they are attached, form a cycloalkyl group; and PA0 R.sup.3 is hydrogen, an alkyl group, or an aryl group, or salts thereof, useful as intermediates in the preparation of HMG-CoA reductase inhibitors; novel methods within the overall process; and novel intermediates produced by those methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.