Basic active component-permeable pressure sensitive adhesive polymer material process of the production thereof and use thereof

US5458885A · kind A · utility

Assignees

• LTS Lohmann Therapie-Systeme GmbH & Co., KG of Germany · DE
• Sandoz AG · CH

Inventors

• Walter Muller · Neuwied, DE
• Zbigniew Czech · Koblenz, DE
• Gunter Simon · Hillesheim, DE
• Joerg Reinhard · Ehrenkirchen, DE

Key dates

• Filing date: Dec 29, 1994
• Grant date: Oct 17, 1995
• Expiry date: Dec 29, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09J2301/302
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A transdermal system employing a basic active component-permeable, pressure sensitive adhesive polymer material, particularly for use with basic active components for use in transdermal administration of systemically or topically acting medicaments constituted by such active components. The adhesive polymer is a homopolymer or copolymer produced using basic monomers preferably on an acrylate base. A process for production of the polymer material comprises mixing monomers suitable for the production of an adhesive by polymerization with basic monomers which can be polymerized and copolymerizing the mixture. The adhesive composition is in particular useful with basic active components in salt form and in which the therapeutically active agent is a Lewis base.