Method and composition for preserving antigens and process for utilizing cytological material produced by same
US5459073A · kind A · utility
60Cited by
40References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 26, 1994 |
| Grant date | Oct 17, 1995 |
| Priority date | — |
| Expiry date | Apr 26, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/108331
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time. The fixative employs a formaldehyde donor that is non-toxic, non-flammable, and that stabilizes the cell with minimal damage to and alteration of the cell morphology. In particular, the cell antigenic sites are left intact so that studies with monoclonal antibodies may be conducted. The invention also discloses a method for developing a positive control for test reagents and for test instrumentation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.