Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5459235A · kind A · utility
31Cited by
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6Claims
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Key dates
| Filing date | Mar 19, 1993 |
| Grant date | Oct 17, 1995 |
| Priority date | — |
| Expiry date | Mar 19, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a new family of cysteine-rich antimicrobial peptides isolated from bovine neutrophils herein named beta defensins. Thirteen structurally homologous peptides were purified to homogeneity from a granule-rich cytoplasmic fraction of purified blood neutrophils. These antimicrobial compounds are useful in human and veterinary medicine, and as agents in agricultural, food science, and industrial applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.