Vasoactive vasotocin derivatives
US5459236A · kind A · utility
5Cited by
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5Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 23, 1992 |
| Grant date | Oct 17, 1995 |
| Priority date | — |
| Expiry date | Sep 23, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to new vasotocin derivatives with prolonged activity compared to previous vasotocin derivatives. In particular, the vasotocin derivatives of the present invention are of the formula (I) ##STR1## wherein Hmp is a 2-hydroxy-3-mercaptopropionic acid residue, ##STR2## Z is Phe or Tyr, Y is Hgn or Hci, X is a residue of the formula ##STR3## wherein Q is H, alanyl or L-2-aminobutyryl and n is 1, 2 or 3. The present invention also relates to pharmaceutical compositions containing these vasotocin derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.