Method for fixing tissues and cells for analysis using oxazolidine compounds
US5460797A · kind A · utility
70Cited by
45References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 3, 1994 |
| Grant date | Oct 24, 1995 |
| Priority date | — |
| Expiry date | Nov 3, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/108331
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time. The fixative employs compounds that are less toxic, non-flammable, and that stabilize the cell with minimal damage to and alteration of the cell morphology. In particular, the cell antigenic sites are left intact so that studies with monoclonal antibodies may be conducted. The invention also discloses a method for developing a positive control for test reagents and for test instrumentation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.