Bioerodible polymers for solid controlled release pharmaceutical compositions
US5461140A · kind A · utility
95Cited by
13References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 15, 1993 |
| Grant date | Oct 24, 1995 |
| Priority date | — |
| Expiry date | Nov 15, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bioerodible ortho ester polymers useful for preparing solid form bioerodible pharmaceutical compositions such as pellets, capsules, suppositories and the like are provided. A novel synthetic method for preparing the polymers is provided as well as is a novel triol reactant. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.