Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives

US5462913A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reiner Fischer · Monheim, DE
• Thomas Bretschneider · Lohmar, DE
• Bernd-Wieland Kruger · Wittlich, DE
• Christoph Erdelen · Leichlingen, DE
• Hans-Joachim Santel · Leverkusen, DE
• Klaus Lurssen · Wittlich, DE
• Robert R. Schmidt · Cologne, DE
• Ulrike Wachendorff-Neumann · Neuwied, DE
• Wilhelm Stendel · Wuppertal, DE

Key dates

• Filing date: Oct 21, 1993
• Grant date: Oct 31, 1995
• Expiry date: Oct 21, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new 1-H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) ##STR1## in which A and B together with the carbon atom to which they are bonded represent a substituted cycle, X represents alkyl, halogen or alkoxy, Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl, Z represents alkyl, halogen or alkoxy, n represents 0, 1, 2 or 3, G represents hydrogen (a) or the groups ##STR2## represents a metal ion equivalent or an ammonium ion, L and M represents oxygen and/or sulphur, R.sup.1 represents in each case optionally halogen-substituted alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, polyalkoxyalkyl or cycloalkyl, which can be interrupted by hetero atoms, optionally substituted phenyl, optionally substituted phenylalkyl, substituted hetaryl, substituted phenoxyalkyl or substituted hetaryloxyalkyl, R.sup.2 represents in each case optionally halogen-substituted alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or in each case optionally substituted phenyl or benzyl, R.sup.3, R.sup.4 and R.sup.5 independently of one another represent in each case optionally halogen-substituted alkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkenylthio, cycloalkylthi…