Cephalosporin compounds
US5462935A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1993 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Feb 10, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a cephalosporin compound represented by formulas (I-S) and (I-R) ##STR1## wherein: R.sup.1 is a C.sub.1-4 alkyl, C.sub.3-4 alkenyl, C.sub.3-4 cycloalkyl, amino optionally substituted with a C.sub.1-4 alkyl radical, phenyl, or 2-,4- or 6- substituted phenyl group with two or fewer substitutents chosen from C.sub.1-4 alkyl, C.sub.1-3 alkoxy, halogen and hydroxy radicals; PA1 R.sup.2 is hydrogen or a C.sub.1-4 alkyl group; PA1 R.sup.a and R.sup.b, which should be different from each other, are hydrogen or a C.sub.1-4 alkyl group; and PA1 Q is N or CH, and the pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates thereof, which possess potent and broad antibacterial activities. The invention also provides processes for preparing these compounds and to pharmaceutical compositions containing them as active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.