Patent · US Expired

1-.beta.-methyl-2-thiolic carbapenem derivatives

US5463046A · kind A · utility

2Cited by
3References
3Claims
0Family size

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Key dates

Filing dateNov 19, 1993
Grant dateOct 31, 1995
Priority date
Expiry dateNov 19, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to new 1-.beta.-methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. ##STR1## The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.