1-.beta.-methyl-2-thiolic carbapenem derivatives
US5463046A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Nov 19, 1993 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Nov 19, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new 1-.beta.-methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. ##STR1## The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.