Method of preparing aryl(homo)piperazines
US5463050A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 12, 1993 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Feb 12, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is concerned with a method for the preparation of a compound of the general formula 2 ##STR1## by reaction of a compound of the formula 3 EQU Ar--Y (3) with a compound of the general formula 4 ##STR2## wherein Ar means a (hetero)aryl group, preferably selected from phenyl, naphtyl, furyl, thienyl, pyridyl, bicylic heteroaryl and tricyclic heteroaryl, which (hetero)aryl group is optionally sustituted with one to five non-strongly-electron-withdrawing substituents; PA1 M is a metal from the groups I or II of the periodic table; PA1 R.sub.12 is an electronegative group; and PA1 is 0 or 1. The invention also relates to compounds prepared according to this method and to new substituted aryl(homo)piperazines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.