Patent · US Expired

Process for the production of 2-ethoxy-4,6-dihydroxypyrimidine or its alkali salts

US5463055A · kind A · utility

2Cited by
4References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 22, 1993
Grant dateOct 31, 1995
Priority date
Expiry dateDec 22, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/60
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A process is described for the production of 2-ethoxy-4,6-dihydroxypyrimidine or its alkali salt which is an important intermediate in the field of pharmaceuticals and agrochemicals. This compound can be produced using the process according to the invention in good yields and high purity by reacting an O-ethylisourea salt that is preferably formed as an intermediate from cyanamide or chloroformamidinium salts or free O-ethylisourea with an alcoholate and a malonic acid dialkyl ester or a salt of the malonic acid dialkyl ester in alcohol and, if desired, subsequent acidification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.