Process for the production of 2-ethoxy-4,6-dihydroxypyrimidine or its alkali salts
US5463055A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1993 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Dec 22, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is described for the production of 2-ethoxy-4,6-dihydroxypyrimidine or its alkali salt which is an important intermediate in the field of pharmaceuticals and agrochemicals. This compound can be produced using the process according to the invention in good yields and high purity by reacting an O-ethylisourea salt that is preferably formed as an intermediate from cyanamide or chloroformamidinium salts or free O-ethylisourea with an alcoholate and a malonic acid dialkyl ester or a salt of the malonic acid dialkyl ester in alcohol and, if desired, subsequent acidification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.