Process for the preparation of aminoaryl .beta.-sulfatoethyl sulfone compounds
US5463100A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 6, 1994 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Sep 6, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C315/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Aminoaryl .beta.-sulfatoethyl sulfone compounds, such as, for example 4-(.beta.-sulfatoethylsulfonyl)-aniline, can be prepared in a quick and easy manner from their corresponding .beta.-hydroxyethyl sulfone compounds by sulfation by spraying a solution or suspension or paste of this aminoaryl .beta.-hydroxyethyl sulfone compound or the acylamino compound thereof in sulfuric acid or aqueous sulfuric acid into a hot inert gas stream of a convection dryer. In this procedure, the drying, esterification reaction and the hydrolysis of any acylamino group present takes place synchronously. The sulfato compound is preferably obtained in the form of granules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.