N-substituted N'-heterobicyclic piperazines having pharmaceutical activity
US5464834A · kind A · utility
18Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 11, 1993 |
| Grant date | Nov 7, 1995 |
| Priority date | — |
| Expiry date | Jun 11, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New N-substituted N'-heterobicyclic piperazines corresponding to the general formula I: ##STR1## wherein: R represents: ##STR2## D represents a single bond, except when R represents naphthyl, or a hydrocarbon chain having 1 to 8 carbon atoms inclusive which is straight-chain or branched by a gem-dimethyl; and A-B represents: --(CH.sub.2).sub.2 --O--, --(CH.sub.2).sub.3 --O--, or --CO--CH.dbd.CH--, as well as their possible stereoisomers, epimers, and pharmaceutically-acceptable acid addition salts thereof; and medicinal products containing the same, useful in the treatment of a disorder requiring a 5-HT.sub.1A receptor antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.