Anion exchanger

US5466368A · kind A · utility

Assignee

• PHARMACIA LKB BIOTECHNOLOGY AB · SE

Inventors

• Lars-Erik Arvidsson · Storvreta, SE
• Hans E. Berg · Uppsala, SE
• Bjorn Engstrom · Sundsvall, SE
• Gunnar Hagstrom · Uppsala, SE

Key dates

• Filing date: Oct 4, 1994
• Grant date: Nov 14, 1995
• Expiry date: Oct 4, 2014

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J39/17
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

An ion exchanger for chromatographic separation has the structure EQU P--S--A, wherein P is an insoluble support, S is a spacer, and A is a functional ligand. According to the invention the functional ligand A comprises two positively charged atoms, each selected from nitrogen and sulphur, at a distance of two atoms from each other, with the proviso that A can not be 4-methyl-1,4-diazabicyclo[2.2.2]octan-1-yl, 1,4,4-trimethylpiperazinium-1-yl, 1,4-dimethyl-1,4-diazabicyclo[2.2.2]octan-2-yl or 1,1,4,4,4-pentamethyl-1,4-diazabutan-1-yl.