Polyiodinated aroyloxy esters

US5466433A · kind A · utility

Assignee

• EASTMAN KODAK COMPANY · US

Inventors

• Edward R. Bacon · East Greenbush, US
• Sol J. Daum · Albany, US
• Paul P. Spara · Fairport, US

Key dates

• Filing date: Jun 20, 1994
• Grant date: Nov 14, 1995
• Expiry date: Jun 20, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C233/91
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds having the structure ##STR1## wherein Z--COO).sub.m is the residue of a polyiodinated aromatic acid; m is 1, 2, 3 or 4; n is an integer from 1 to 20; R.sup.1 and R.sup.2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R.sup.3 and R.sup.4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; and R.sup.5 is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods.