Method of diagnosing fatty acid metabolism or absorption disorders using labeled triglyceride oils produced by cultivation of microorganisms
US5466434A · kind A · utility
16Cited by
2References
11Claims
0Family size
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Inventor
Key dates
| Filing date | Nov 10, 1994 |
| Grant date | Nov 14, 1995 |
| Priority date | — |
| Expiry date | Nov 10, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/946
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Labelled triglyceride oils are produced for use in diagnostic breath test. The process involves the cultivation of microorganisms capable of producing the oils in an appropriately controlled environment wherein the microorganisms are fed .sup.13 C or .sup.14 C labeled carbon substrates to induce the microorganisms to produce the labeled oils. The preferred labelled carbon substrate is a substrate containing .sup.13 C. The oil produced is preferrably enriched in oleic acid. The microorganisms can be induced to produce the oil by nitrogen depletion during cultivation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.