Formulations of oral gastrointestinal diagnostic X-ray contrast agents in combination with pharmaceutically acceptable clays
US5466440A · kind A · utility
56Cited by
8References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 30, 1994 |
| Grant date | Nov 14, 1995 |
| Priority date | — |
| Expiry date | Dec 30, 2014 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nanoparticulate crystalline substances formulated with stabilizers and pharmaceutically acceptable clays to enhance contact between the crystalline substances and the gastrointestinal tract. These formulations have improved safety profiles, a low potential for absorption, are not viscous and are not contraindicated for GI perforations or intestinal obstructions. The properties of the surfactant stabilizers are independent of the crystalline drug used and largely determine the extent to which the formulation coats the GI tract.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.