Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation

US5466687A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Roland Maier · Biberach an der Riß, DE
• Peter Muller · Mittelbiberach, DE
• Eberhard Woitun · Biberach an der Riß, DE
• Rudolf Hurnaus · Großenhain, DE
• Michael Mark · Biberach an der Riß, DE
• Bernhard Eisele · Biberach, DE
• Ralph-Michael Budzinski · Biberach, DE
• Gerhard Hallermayer · Biberach an der Riß, DE

Key dates

• Filing date: Mar 25, 1994
• Grant date: Nov 14, 1995
• Expiry date: Mar 25, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula ##STR1## (wherein n, m, p, A, W.sup.1, W.sup.2, X, Y, and R.sup.1 to R.sup.11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.