8-phenyl-1,6-naphthyridin-5-ones
US5466697A · kind A · utility
19Cited by
1References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 1994 |
| Grant date | Nov 14, 1995 |
| Priority date | — |
| Expiry date | Jul 13, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosed 8-aryl-1,6-naphthyridin-5-ones, compounds of Formula I, ##STR1## wherein: R.sub.1 is hydrogen, alkyl, lower alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkyl lower alkyl, heterocycloalkyl lower alkyl, aralkyl or heteroaralkyl; and PA1 R.sub.2 is aryl; or a pharmaceutically acceptable salt or N-oxide thereof are useful as anti-inflammatory agents, immunosuppressive agents, anti-allograft rejection agents, anti-graft-vs-host disease agents, anti-allergic agents (e.g., asthma, rhinitis and atopic dermatitis), bronchodilation agents, anti-autoimmune agents or analgetic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.