Patent · US Expired

Tetrazole derivatives of bile acids, and their use as lipid level lowering medicaments

US5466815A · kind A · utility

25Cited by

1References

8Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Alfons Enhsen · Lennestadt, DE
Heiner Glombik · Hofheim, DE
Werner Kramer · Schwandorf, DE
Gunther Wess · Niederrodenbach, DE

Key dates

Filing date	May 5, 1994
Grant date	Nov 14, 1995
Priority date	—
Expiry date	May 5, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J43/003
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to tetrazole derivatives of bile acids, processes for their preparation, and use of these compounds as medicaments and cholesterol lowering agents. The tetrazole-bile acid derivatives are of the formula G1--X--G2, where G1 is H, a bile acid radical, or a bile acid radical which is modified on the hydroxyl functions and/or on the carboxyl group, X is a single bond or a bridge group between G1 and G2, and G2 is of the formula: ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.