Patent · US Expired

Low carryover pipette probe

US5468453A · kind A · utility

36Cited by
8References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 1993
Grant dateNov 21, 1995
Priority date
Expiry dateJun 14, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/2575
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An improved pipette probe in an automated chemical analysis system is provided, along with a pipette tip wash protocol to reduce carryover. The pipette tip comprises an elongated stainless-steel barrel which houses a polytetrafluoroethylene tube. The non-wettable properties of polytetrafluoroethylene inhibit fluid adhesion and thereby reduce carryover. The pipette tip is swaged at a fluid dispensing end to a restrictive diameter for good pipetting precision and accuracy. A novel wash protocol is also provided which includes a novel wash solution comprising quantities of Triton X-100 nonionic detergent, Diethanolamine, and NaCl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.