Patent · US Expired

Pharmaceutical composition of purified chymopapain

US5468480A · kind A · utility

10Cited by
7References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 8, 1994
Grant dateNov 21, 1995
Priority date
Expiry dateSep 8, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmaceutical composition comprising purified chymopapain and a reducing agent is presented. The purified chymopapain in this composition has a specific activity against 1 mM of N-.alpha.-benzoyl-DL-arginine p-nitroanilide at 40.degree. C. and pH 6.8 of between 3,000 and 4,500 units per mg, and contains less than 0.2% each of papaya proteinase III (PPIII), papain, and papaya proteinase IV (PPIV).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.