Liposomes containing the salt of phosphoramide mustard and related compounds
US5468499A · kind A · utility
8Cited by
13References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 15, 1993 |
| Grant date | Nov 21, 1995 |
| Priority date | — |
| Expiry date | Nov 15, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1271
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an anti cancer treatment which has an improved stability and does not produce acrolein. The invention includes dichlorodiethyl phosphoramide drugs including, for example, the cyclohexylamine salt phosphoramide mustard and isophosphoramide mustard and mixtures thereof, which have been entrapped by liposomes. Preferably the liposomes contain sphingomyelin and cholesterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.