N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents

US5468858A · kind A · utility

Assignee

• The Board of Regents of Oklahoma State University Physical Sciences · US

Inventors

• Kenneth D. Berlin · Stillwater, US
• Gregory Lynn Garrison · Chelmsford, US
• Subbiah Sangiah · Stillwater, US
• Cyril Clarke · Perkins, US
• Chun-Lin Chen · Taipei, TW
• Ralph Lazzara · Oklahoma City, US
• Benjamin J. Scherlag · Oklahoma City, US
• Eugene Patterson · Oklahoma City, US
• George Edward Burrows · Stillwater, US

Key dates

• Filing date: Oct 28, 1993
• Grant date: Nov 21, 1995
• Expiry date: Oct 28, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

3,7-Diazabicyclo[3.3.1]nonanes and selected derivatives thereof of the general formula: ##STR1## are disclosed as multiclass antiarrhythmic agents.