Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines
US5468876A · kind A · utility
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Key dates
| Filing date | Feb 24, 1994 |
| Grant date | Nov 21, 1995 |
| Priority date | — |
| Expiry date | Feb 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are (R)- and (S)-isomers of the compounds of the Formulas II and III with at least 95% optical purity ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and represent a hydrogen atom, a lower alkyl, lower alkenyl or lower alkynyl group, a cycloalkyl group or a group (CH.sub.2).sub.m Ph, wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group. These compounds are intermediates in the stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.