Microsphere drug application device

US5470311A · kind A · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• Jean A. Setterstrom · Silver Spring, US
• Elliot Jacob · Silver Spring, US
• Walter FRANZ · Seßlach, DE

Key dates

• Filing date: May 24, 1994
• Grant date: Nov 28, 1995
• Expiry date: May 24, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1647
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Apparatus and methods for dispensing medicinals encapsulated in a biodegrble polymer in surgical and other wounds are described. The apparatus, a microcapsule drug applicator, allows the caregiver to implant or spread measured and uniform quantities of microencapsulated medicinals in or on surgical or traumatic wounds to prevent and/or treat infections. Specific examples where microencapsulated antibiotics may prove useful include, soft-tissue wounds, following debridement and reduction or fixation of open fractures, to osteomyelitic bone after surgical debridement, after surgical insertion of prostheses such as hip/knee replacements (arthroplasty), and following vascular surgery or grafting.