Detection of appendicitis by measurement of orthohydroxyhippuric acid
US5470750A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 9, 1992 |
| Grant date | Nov 28, 1995 |
| Priority date | — |
| Expiry date | Jul 9, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Appendicitis can be detected in human beings suspected of having appendicitis by determining a threshold level of 10 mg/liter of .sigma.-hydroxyhippuric acid in the urine of such humans. This threshold level can be determined by qualitative, semiquantitative, or quantitative methods including HPLC (high pressure liquid chromatography), TLC (thin layer chromatography), radioimmunoassay, colorimetric tests, NMR (nuclear magnetic resonance), mass spectrometry, electrophoresis, monoclonal antibody tests, and enzymatic tests. The absence of appendicitis can be established by the presence of .sigma.-hydroxyhippuric acid in concentrations less than about 10 mg/liter in a urine sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.