Carbohydrate-containing polymers, their preparation and use

US5470843A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Wilhelm Stahl · Idstein, DE
• Michael Ahlers · Mainz, DE
• Axel Walch · Baldham, DE
• Eckhart Bartnik · Wiesbaden, DE
• Gerhard Kretzschmar · Eschborn, DE
• Susanne Grabley · Königstein, DE
• Rudolf Schleyerbach · Hofheim, DE

Key dates

• Filing date: Dec 13, 1993
• Grant date: Nov 28, 1995
• Expiry date: Dec 13, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Carbohydrate-containing polymers which can have an HLB* of from about 10 to about 20 are disclosed. The compounds comprise a hydrophilic polymer portion, a carbohydrate portion comprising from 1 to about 20 naturally occurring, identical or different, monosaccharide units, at least one bifunctional spacer coupling the carbohydrate portion to the hydrophilic polymer portion, and a potentiator moiety. The potentiator moiety can be is a crosslinking moiety located within the hydrophilic polymer or a hydrophobic, hydrophilic or ionic moiety. Processes for the preparation and use of such polymers are also disclosed.