Patent · US Expired

Derivatives of (hetero)aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them

US5470858A · kind A · utility

1Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 19, 1992
Grant dateNov 28, 1995
Priority date
Expiry dateJun 19, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound represented by the following formula I: EQU (HET)Ar--X--CH.sub.2 --Y--CH.sub.2 --O--R (I) wherein: PA1 (HET)Ar represents a bicyclic hetero aryl nucleus which is unsubstituted or is substituted; PA1 X represents --S--; PA1 Y represents --CO--, --C.dbd.N--R.sub.2, in which R.sub.2 is hydrogen or a linear or branched alkyl having 1 to 10 carbon atoms, OH, an alkoxy having 1 to 10 carbon atoms, aryloxy, arylalkoxy, --NH.sub.2, --NHCONH.sub.2, --NHCSNH.sub.2 ; and R represents a phenyl substituted at para position with a carboxyl or a (C.sub.1 -C.sub.20) alkoxycarbonyl group in which the alkoxy group is linear or branched.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.