Asymmetric synthesis of bicyclic amino acid esters
US5470979A · kind A · utility
1Cited by
1References
20Claims
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Inventor
Key dates
| Filing date | Jul 1, 1994 |
| Grant date | Nov 28, 1995 |
| Priority date | — |
| Expiry date | Jul 1, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D217/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention is an improved process for producing an optically active compound of formula IV: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.4 are herein described. The improved process to produce a compound of formula IV comprises: PA0 a). reacting a diene with a chiral compound, containing a chiral auxiliary to obtain an olefinic compound; PA0 b). removing the chiral auxiliary and reducing the olefin by hydrogenation to obtain a compound of formula IV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.