Patent · US Expired

Pharmaceutical controlled-release composition with bioadhesive properties

US5472704A · kind A · utility

157Cited by

5References

23Claims

0Family size

Assignee

Recordati S.A. Chemical and Pharmaceutical Company · CH

Inventors

Giancarlo Santus · Milano, IT
Giuseppe Bottoni · Bologna, IT
Giovanni Sala · Verona, IT

Key dates

Filing date	Dec 27, 1993
Grant date	Dec 5, 1995
Priority date	—
Expiry date	Dec 27, 2013

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/5089
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical composition for the controlled release of medicinal drugs, which has the property of adhering to biologic tissues is described. The characteristic features of the composition are a plurality of small-size units capable of ensuring a gradual release of the active ingredient they contain the units being coated with a bioadhesive polymer layer. The composition makes it possible to keep the release controlling function separate from the function providing bioadhesion and can be adapted inter alia to oral, ocular, rectal, vaginal, nasal or periodontal administrations. An advantageous process for making the composition is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.