Patent · US Expired

Substituted benzoate derivatives

US5473096A · kind A · utility

1Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 21, 1993
Grant dateDec 5, 1995
Priority date
Expiry dateJul 21, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C229/38
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the compounds of the formula: ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 are independently hydrogen, lower alkyl which is optionally substituted, lower alkoxy which is optionally substituted, hydroxy, acyloxy, or halogen; R.sup.9 is hydrogen, hydroxy, acyloxy, lower alkyl which is optionally substituted, lower alkoxy which is optionally substituted, or lower alkylamino which is optionally substituted; E.sup.1 is hydrogen, or an ester residue; m is an integer of from 1 to 4; or a pharmaceutically acceptable salt thereof. The compounds of the present invention exhibit phospholipase A.sub.2 inhibitory activity, and can be used in treating inflammatory conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.