Treatment of microbial infection by monocyte stimulation with interleukin-7
US5474769A · kind A · utility
4Cited by
3References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 12, 1993 |
| Grant date | Dec 12, 1995 |
| Priority date | — |
| Expiry date | Nov 12, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/2046
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is disclosed a method of treating microbial infections in microbially infected mammals and a method of augmenting antitumor immunotoxicity in a mammal comprising administering a therapeutically effective amount of IL-7 in a pharmaceutically acceptable carrier. There is further disclosed a method of stimulating macrophages to produce cytokines made by activated macrophages and a method for improving T cell presentation by a macrophage comprising administering a therapeutically effective amount of IL-7. Further, antimicrobial activity of macrophages can be improved by administering a combination of IL-7 and Interferon-.gamma..
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.