Plasma-based platelet concentrate preparations with additive
US5474891A · kind A · utility
58Cited by
10References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 16, 1994 |
| Grant date | Dec 12, 1995 |
| Priority date | — |
| Expiry date | Jun 16, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N1/126
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a composition and method for improving the storage of platelets and optimizing the viability of stored platelets. The present invention allows platelets to be stored in plasma for extended periods, without the addition of buffer, by adding storage extension additives, which include acetate, pyruvate, acetoacetate, .beta.-hydroxybutyrate, acetone, .alpha.-ketoglutarate, succinate, fumarate, malate, oxaloacetate, C.sub.3-8 fatty acid anions, triose phosphates and mixtures thereof, to a platelet concentrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.