Antibodies specific for streptococcus pneumoniae hemin/hemoglobin-binding antigens
US5474905A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1993 |
| Grant date | Dec 12, 1995 |
| Priority date | — |
| Expiry date | Nov 24, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the isolation of newly discovered hemin/hemoglobin-binding proteins of Streptococcus pneumoniae with approximate molecular weights of 18, 43, 55, 66 and 76 kDa, respectively, thereby providing bacterial-derived antigens and active derivatives and parts thereof, useful in the diagnostic assays, vaccines and pharmaceutical compositions relative to these bacteria. In addition, the present invention is directed to polyclonal and monoclonal antibodies directed to the hemin/hemoglobin-binding proteins of Streptococcus pneumoniae. The present invention further relates to methods of diagnosing and treating human pneumococcal infections including kits therefor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.