Complement components and binding ligands in fertility
US5474927A · kind A · utility
5Cited by
3References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1993 |
| Grant date | Dec 12, 1995 |
| Priority date | — |
| Expiry date | Oct 19, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/852
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for detecting and isolating acrosome-reacted sperm and complement receptor-bearing oocytes using the complement component C3, fragments, or variants thereof, antibodies to a complement receptor, or antibodies to C3, are disclosed. These methods have application in the assessment of fertility, in the preparation of sperm or oocytes for in vitro fertilization or for gamete intrafallopian tube transfer, in promoting or inhibiting fertilization in vitro and in vivo, and in diagnosing and treating infertility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.