Intestine colonizing strains of lactobacilli

US5474932A · kind A · utility

Assignee

• PROBI AB · SE

Inventors

• Stig Bengmark · Lund, SE
• Siv Ahrne · Bjärred, SE
• Goran Molin · Bjärred, SE
• Bengt Jeppson · Lund, SE

Key dates

• Filing date: Apr 16, 1993
• Grant date: Dec 12, 1995
• Expiry date: Apr 16, 2013

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/857
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for isolation of a strain of Lactobacillus having the ability of being established on human intestinal mucosa in vivo and being able to remain therein after oral administration for at least 10 days after the completion of the administration. By the process the new strains L. plantarum 299 (DSM 6595) and L. casei ssp. rhamnosus 271 (DSM 6594) have been isolated, which are useful for the prophylaxis or treatment of bacterial infections, especially in the form of a fermented nutrient composition.