Nucleic acid ligands
US5475096A · kind A · utility
536Cited by
2References
43Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 1991 |
| Grant date | Dec 12, 1995 |
| Priority date | — |
| Expiry date | Jun 10, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A new class of nucleic acid compounds, referred to as nucleic acid ligands, have been shown to exist that have a specific binding affinity for three dimensional molecular targets. In a preferred embodiment the nucleic acid ligands are identified by the method of the invention referred to as the Systematic Evolution of Ligands by EXponential enrichment (SELEX), wherein a candidate mixture of nucleic acids are iteratively enriched in high affinity nucleic acids and amplified for further partitioning.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.