Peptide production
US5476995A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 1992 |
| Grant date | Dec 19, 1995 |
| Priority date | — |
| Expiry date | Aug 18, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing a proteinaceous compound, involves incorporating a DNA sequence coding for polypeptide into a gene of a mammal (such as a sheep) coding for a milk whey protein in such a way that the DNA sequence is expressed in the mammary gland of the adult female mammal. The proteinaceous compound may be a (optionally modified) protein such as a blood coagulation factor. The DNA sequence is preferably inserted into the first exon of a gene coding for a whey protein such as beta-lactoglobulin. The proteinaceous compound will generally be recovered from milk of the female mammal, but may (for example if it is an enzyme) be used in situ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.