Process for the preparation of substantially alcohol free pharmaceutical compositions
US5478571A · kind A · utility
3Cited by
10References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 1995 |
| Grant date | Dec 26, 1995 |
| Priority date | — |
| Expiry date | Jan 17, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel process for the preparation of pharmaceutical compositions involving the stabilization of the active drug(s) through the reduction of residual alcohol present in a drug/carrier blend. The presence of residual alcohol in dried pharmaceutical compositions adversely affects many drugs which must be initially dissolved therein in order to achieve uniform distributions throughout the excipient carrier materials. Wherein not previously possible, its removal is achieved utilizing precise processing parameters in which water lost during the drying process is replenished during blending in a conventional solids processor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.